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Dois dos principais candidatos, no entanto. são os fatores de transcrição T-boxTbet (Te -caixas expressa em sporting bet baixar células A) e Eomesodermina (Eomes).A T-bet é expressa em: CD4+ +células do tipo 1 (Th1), CD8+ +EE células célula celulares, células dendríticas (DCS) e natural killer(NK). T células.
De forma semelhante, Barnett eT al. descobriram que oAs células B que expressam T-bet beting são necessárias para o vírus da coriomeningite linfocítica (LCMV) específico IgG2a. produçãoe são dispensáveis durante a infecção aguda, mas necessários para o controle da infecções crônica;39 39.
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